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Evaluation of a Simple Automated Bioreactor for the Production of Pelargoniums Progress Report –September 1993

Date August 1993

Title of Project Evaluation of a Simple Automated Bioreactor for the Production of Pelargoniums

Institution where work is being conducted Department of Horticulture, Penn State University

Amount of Endowment Grant $ 5000
Covering Period Dec. 1993 to Nov. 1993

Anticipated Date of Project Completion/Final Report November 1996

Individual(s) Conducting Project:

(List Project Leader First)

Richard N. Arteca - Title Professor

Telephone Number (814) 863-2252

Evaluation of a Simple Automated Bioreactor for the Production of Pelargoniums

Richard N. Arteca

Pennsylvania State University

Progress Report to the American Floral Endowment, 8/93
A. Project Objectives:
Our major objectives for the second year of this project were to:
1. Manipulate environmental conditions, plant hormone amounts/ratios and othermedia supplements to promote maximum growth of callus and cell suspensions;

2. Induce plantlet formation and maximize the number of plantlets formed withdifferent hormone treatments in callus and cell suspension cultures;

3. To induce root formation on plantlets with different hormone treatments and growplants in tissue culture to increase the size prior to transfer to the greenhouse where they

will first be acclimated and then grown to flowering;

4. To evaluate different cryopreservation and low temperature storage methods for ourdifferent cell lines.

B. Summary of Work Conducted:
The results reported within this progress report are suitable for dissemination.
C. Results to Date:
Our work over the past six months (March 93 to September 93) has been to manipulateconditions to maximize the growth rates, shoot and root formation in our callus and

suspension culture lines and to use different cryoprotectants in order to cryopreserve

existing cell lines. We have been successful in maximizing growth rates of our suspension

cultures by modifying environmental conditions, plant hormone amounts/ratios and other

media supplements to promote maximum growth of the callus and suspension cultures

while still maintaining chromosome stability. AR attempts thus far have been unsuccessful

in cryopreserving either callus or suspension culture lines, however, we are still working

on this. A temporary solution to this problem has been to place the callus or suspension

cultures at reduced temperatures to suppress their growth. We have been successful in

keeping the cultures at 12′C which dramatically reduces their growth rates. When the

cultures are transferred to 20′C they win grow at the same rate as prior to low temperature

treatments and maintain chromosome stability. We are presently evaluating lower

temperatures and the stability of these cultures over longer periods of time. We have been

successful in the induction of organogenic callus, however, our major stumbling block to

date has been our inability to grow adequate numbers of rooted plants per gram of callus in

order to proceed to the greenhouse and to start bioreactor work. While we have been

successful in obtaining some small plantlets only a very small percentage of these will

develop roots and enlarge to sufficient size for transfer to the greenhouse. The plants

which do grow to an adequate size will readily acclimate to greenhouse conditions.

D. Future Plans Covered by the Endowment Grant:
Our goals for the remainder of the 1992 to 1993 research year are to manipulateconditions to maximize the number of shoots per gram of callus and to induce root

formation in these shoots. To use different cryoprotectants in order to cryopreserve our

existing cell lines and to continue to evaluate the potential of low temperature storage of our

cultures. The proposed experiments for the 1993-1994 research year are to do the

following:

1. Maximize the number of plantlets per gram of tissue with different hormonetreatments in callus and cell suspension cultures;

2. To induce root formation on plantlets with different hormone treatments and growplants in tissue culture to increase the size prior to transfer to the greenhouse where they

will first be acclimated and then grown to flowering;

3. To evaluate different cryopreservation and low temperature storage methods for ourdifferent cell lines.

After these goals are achieved we will evaluate bioreactor technology for the productionof Pelargonium plants. This will be accomplished by seeding an airlift bioreactor with cells

grown in suspension culture and do the following:

- treat with hormones to promote maximum growth of callus;
soil and grow.

The last phase of this project will be to design a larger bioreactor and evaluate how initialstudies work on a commercial scale.

At the present time the major problem which we are encountering is that the number ofshoots formed per gram of callus is very low and before scaling up to a bioreactor this

problem must be solved. It may appear to be a trivial problem, however, this is the reason

why Pelargoniums now propagated by cuttings are not commercially grown in tissue

culture. We are confident that we can overcome this problem, in fact, the entire project

should be successfully completed within the proposed four year period, since at the present

rate of progress we are keeping up with the schedule initially proposed.

E. Anticipated Benefits for Floral Industry:
The overall goal of the proposed research is to develop an automated bioreactor whichcan be used to increase the commercial production of selected Pelargoniums with desired

characteristics such as new genotypes or disease-free plants rapidly and efficiently. The

availability of such methods will also lead to increased breeding and selection efforts which

in turn will promote increased quality of Pelargoniums at a reduced cost which is a true

benefit to the floral industry.