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Control of Tomato Spotted Wilt Virus in Floral Crops Progress Report — March 1992

Date February 19, 1992

Title of Project Control of Tomato Spotted Wilt Virus in Floral Crops

Institution where work is being conducted North Carolina State University

Amount of Endowment Grant $ 35,000
Covering Period Jan. 1992 to Dec. 1992

Anticipated Date of Project Completion/Final Report December 1992

Individual(s) Conducting Project:

(List Project Leader First)

James Moyer - Title Professor

Telephone Number 919-515-2735

Control of Tomato Spotted Wilt Virus in Floral Crops

James Moyer

North Carolina State University

Progress Report to the American Floral Endowment, 2/19/92

A. Project Objectives:

The original proposal contained four objectives; 1) To collect TSWV-Iike

isolates from different floral crop hosts and geographic regions. 2) Develop biological and

biochemical assays for these virus-host combinations. 3) Compare the biological and biochemical

properties of floral crop-specific isolates with each other and with standard isolates of TSWV. 4)

To develop resistance to these viruses in floral crops.

B. Overall Summary:

Our early research focused on the identification and characterization of the

TSWV-like viruses found in floral crops. We identified a new virus which has been named

Impatiens necrotic spot virus (formerly TSWV-I). This was the first report of serological diversity

in the TSWV group of viruses and was recently cited in a review of the highlights of virology (plant

and animal) for 1990. Antiserum was made for diagnostic and research purposes. We have also

collected approximately twenty TSWV-like isolates from floral crops from all over the United

States. These played an important role in improving our diagnostic tools, in providing an accurate

representation of the TSWV-like isolates in the floral crop industry and will be invaluable in

testing resistant cultivars. We have tested diagnostic approaches, both biological and serological,

developed in our lab and those developed and recommended by others for use in routine diagnosis

and for clean stock programs. Much of this information has been put to use not only by ourselves,

but also by diagnosticians in public and private plant disease clinics. We have also conducted a

thorough comparison of the different isolates. Host range studies have been completed and a

student (not supported by this grant) is currently conducting a detailed serological analysis with

polyclonal and monoclonal antibodies. A significant finding of his research is that a monoclonal

antibody which reacts with both L and I types has been identified which will hopefully lead to a

single test for all TSWV-like isolates. We have also completed the biochemical characterization of

the TSWV isolate and isolated viral genes from both serotypes which can be used to impart

resistance to these viruses. Most recently we have emphasized the development of transformation

protocols for chrysanthemum and New guinea Impatiens. Thus, we have essentially completed

Objectives 1 - 3 and initiated investigations on Obj. 4. Manuscript status is attached.

C. Recent Results and Future Activity:

Research on transformation of chrysanthemum has

continued. Regeneration procedures for obtaining plants from leaf discs were available for two

cultivars; Hekla and Iridon. Quite recently we have had some preliminary success in transforming

Iridon with a reporter gene. Current transformation efforts are using the TSWV resistance gene.

We have also been extending these efforts to include TSWV susceptible cultivars such as Polaris.

We have developed a regeneration procedure for this cultivar as available procedures were

ineffective. We have also initiated attempts to develop a transformation system for New Guinea

Impatiens. This has been somewhat more problematic as there was no regeneration system

available suitable for transformation. Thus, we have had to begin at the very beginning. Prolific

rooting of leaf tissue explants was an initial problem, but has been overcome. We have also

overcome problems with contamination. Hormone requirements which promote callus formation

and suppress root formation have been identified. Current efforts consist of identifying hormone

requirements for shoot initiation and evaluation of strains of Agrobacterium which are used to

mediate the transformation process.

D. Anticipated Benefits for Floral Industry:

Our research on the nature of these viruses has provided the

basis for diagnosis. The antisera, in a kit format, is commercially available through Agdia, Inc.

Research underway way is anticipated to lead to one kit for all TSWV-like viruses. Our current

research is directed at developing procedures for the introduction of virus resistance genes into

important floral crops. These techniques will also be applicable for the introduction of other genes

such as resistance to other viruses, herbicide tolerance, insect resistance and control of ethylene

production.

E. Status of Research Publications Supported All or In Part by the American Floral Endowment:

Law, M. D., and J. W. Moyer. 1989. Physicochemical analysis of a serologically distinct tomato

spotted wilt virus strain. Phytopathology 79:1157 (abstract).

*Law, M. D. and J. W. Moyer. 1990. A tomato spotted wilt-like virus with a serologically distinct

N protein. J. General Virology 71:933-938. (cited in highlights in virology for 1990 covers both

plant and animal viruses).

**Urban, L., Huang, P., and J. W. Moyer. 1991. Cytoplasmic inclusions in cells infected with

isolates of the L- and I- serogroups of tomato spotted wilt virus. Phytopathology 81:521-525.

***Law, M. D., Speck, J., and J. W. Moyer. 1991. Nucleotide sequence of the Tnon-coding region

and N gene of the S RNA of a serologically distinct tospovirus. J. of Gen. Virol. 72:2597-2601.

***Law, M. D., Speck, J., and J. W. Moyer. 1992. The M RNA of Impatiens Necrotic Spot

Tospovirus (Bunyaviridae) has an ambisense genomic organization. Virology Submitted.

Urban, L. A., Sherman, J. M., Moyer, J. W. and Daub, Margaret, E. 1992. Regeneration and

Agrobacterium-mediated transformation of Chrysanthemum trifoliar. In-Vitro Culture and

Horticulture Breeding Symposium. Submitted.

* Original description of TSWV-I type virus.
** Part of the comparison of TSWV-Iike viruses. This aspect has been given to a student on state

support and will be published soon. AFE support will be acknowledged.

*** These papers describe the gene to be used for resistance to the I type virus.
- Manuscript describing monoclonal antibody which reacts with both TSWV and INSV (formerly

TSWV-I) is in preparation.